Dengue, Antigen NS1

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Test Description

The type of testing performed is typically dictated by the timing and volume of samples available. Blood test is the only reliable way to identify chikungunya since the symptoms are similar to much more deadly dengue fever.

Symptoms include fever and joint pain. These typically occur two to twelve days after exposure. Other symptoms may include headache, muscle pain, joint swelling, and a rash. 

Exclusion from childcare, preschool, school or work is usually not necessary but people experiencing fever from dengue infection should not be in an environment where they may be bitten by mosquitoes. If this is not possible they should stay at home until they have no fever and are therefore no longer infectious (usually 3 to 5 days). 

There is no vaccine to prevent human infection by this virus. 

Personal protection and the environmental management of mosquitoes are important in preventing illness. 

Prevent access of mosquitoes to an infected person with a fever. 

Protect yourself from mosquito bites at all times in dengue areas. For tips on how to protect yourself, see Fight the Bite. 

Because no approved vaccine exists, the most effective means of prevention are protection against contact with the disease-carrying mosquitoes and controlling mosquito populations by limiting their habitat. Mosquito control focuses on eliminating the standing water where mosquitos lay eggs and develop as larva; if elimination of the standing water is not possible, insecticides or biological control agents can be added. Methods of protection against contact with mosquitos include using insect repellents with substances such as DEET, icaridin, PMD (p-menthane-3, 8-diol, a substance derived from the lemon eucalyptus tree), or IR3535. However, increasing insecticide resistance presents a challenge to chemical control methods.

Test Method 1 : RT-PCR

Viral RNA can be easily detected by reverse transcriptase-polymerase chain reaction (RT-PCR) in serum specimens obtained from patients during the acute phase of infection. Chikungunya infections cause high levels of viremia (up to 1x10E6. 8 plaque-forming units per mL), which typically last for 4_6 days after the onset of illness. RT-PCR can therefore easily been done within the first 7 days on an acute-phase specimen to confirm chikungunya virus infection. RT_PCR products from clinical samples may also be used for genotyping of the virus, allowing comparisons with virus samples from various geographical sources. PCR results can be available within one to two days. 

Report available : Turn around time is 1 to 2 days. 

Currently, no specific treatment for chikungunya is available. Supportive care is recommended, and symptomatic treatment of fever and joint swelling includes the use of nonsteroidal anti-inflammatory drugs such as naproxen, non-aspirin analgesics such as paracetamol (acetaminophen) and fluids. Aspirin is not recommended due to the increased risk of bleeding. Despite anti-inflammatory effects, corticosteroids are not recommended during the acute phase of disease, as they may cause immunosuppression and worsen infection. 

A person have the following signs and symptoms should get this done: 

Symptoms include fever and joint pain. These typically occur two to twelve days after exposure. Other symptoms may include headache, muscle pain, joint swelling, and a rash. 

Gender : Mainly occurs in child, younger and older persons. 

Age : Mainly occurs at the age 5 to 65 years. 

Socio Geographic :  The disease typically occurs in Africa and Asia, outbreaks have been reported in Europe and the America. 

Liver, brain
Dengue fever