Creatinine Kinase (CPK)

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Test Description

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys are working.

symptoms include: 

fatigue and trouble sleeping

a loss of appetite

swelling in the face, wrists, ankles, or abdomen

lower back pain near the kidneys

changes in urine output and frequency

high blood pressure



A high CK, or a rise in levels in subsequent samples, generally indicates that there has been some recent muscle damage but will not indicate its location or cause. Serial test results that peak and then begin to drop indicate that new muscle damage has diminished, while increasing and persistent elevations suggest continued damage.

Increased CK levels may be seen in some muscular disorders (myopathies), which have a wide variety of causes. People may have CK levels that are significantly to greatly increased, depending upon the severity of muscle damage. Those who have rhabdomyolysis may have CK levels that are 100 times normal levels and occasionally even higher.

Increased CK may be seen with, for example:

Recent crush and compression muscle injuries, trauma, burns, and electrocution

Inherited myopathies, such as muscular dystrophy

Hormonal (endocrine) disorders, such as thyroid disorders, Addison disease or Cushing disease

Strenuous exercise

Prolonged surgeries


Infections _ viral (such as influenza and HIV), bacterial, fungal, and parasitic (such as malaria)

Connective tissue disorders (e.g. lupus, rheumatoid arthritis)

Celiac disease

Renal failure

In critically ill patients

High fever accompanied by shivering

A blood clot (thrombosis) blocking the flow of blood

Any drug or toxin that interferes with muscle energy production or increases energy requirements

Normal CK levels may indicate that there has not been muscle damage or that it occurred several days prior to testing.

Moderately increased CK levels may be seen following strenuous exercise such as in weight lifting, contact sports, or long exercise sessions.

Control your blood sugar if you have diabetes. Keep a healthy blood pressure. Follow a low-salt, low-fat diet. Exercise at least 30 minutes on most days of the week. Keep a healthy weight. Do not smoke or use tobacco. Limit alcohol.

Test Method 1 : The test requires a blood sample, which is drawn through a needle from a vein in your arm. 

Report available : Turn around time is 24 hours. 

Kidney disease complications can be controlled to make you more comfortable. Treatments may include: 


High blood pressure medications. People with kidney disease may experience worsening high blood pressure. Your doctor may recommend medications to lower your blood pressure „ commonly angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers „ and to preserve kidney function. High blood pressure medications can initially decrease kidney function and change electrolyte levels, so you may need frequent blood tests to monitor your condition. Your doctor will likely also recommend a water pill (diuretic) and a low-salt diet. 

Medications to lower cholesterol levels. Your doctor may recommend medications called statins to lower your cholesterol. People with chronic kidney disease often experience high levels of bad cholesterol, which can increase the risk of heart disease. 

Medications to treat anemia. In certain situations, your doctor may recommend supplements of the hormone erythropoietin (uh-rith-roe-POI-uh-tin), sometimes with added iron. Erythropoietin supplements aid in production of more red blood cells, which may relieve fatigue and weakness associated with anemia. 

Medications to relieve swelling. People with chronic kidney disease may retain fluids. This can lead to swelling in the legs, as well as high blood pressure. Medications called diuretics can help maintain the balance of fluids in your body. 

Medications to protect your bones. Your doctor may prescribe calcium and vitamin D supplements to prevent weak bones and lower your risk of fracture. You may also take medication known as a phosphate binder to lower the amount of phosphate in your blood, and protect your blood vessels from damage by calcium deposits (calcification). 

A lower protein diet to minimize waste products in your blood. As your body processes protein from foods, it creates waste products that your kidneys must filter from your blood. To reduce the amount of work your kidneys must do, your doctor may recommend eating less protein. Your doctor may also ask you to meet with a dietitian who can suggest ways to lower your protein intake while still eating a healthy diet. 

A person have the following symptoms should get this done: 

fatigue and trouble sleeping

a loss of appetite

swelling in the face, wrists, ankles, or abdomen

lower back pain near the kidneys

changes in urine output and frequency

high blood pressure



Gender : Mainly occurs in males. 

Age : Mainly occurs at the age of 45 to 60. 

Socio Geographic : It is predominant all over the world specially in third word countries. 

Brain, nerve cells
Blocked urinary tract Kidney problems seizures, preeclampsia