Coombs Test - Direct (DCT)

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Know more about Coombs Test - Direct (DCT)

The Coombs test checks for certain antibodies that are present in the blood.

Symptoms that may include: 

Pale appearance

Jaundice, including elevated bilirubin

Enlarged liver or spleen

Swelling of the entire body

Difficulty breathing

Signs and symptoms of a blood transfusion reaction are: 

Fever, chills

Back pain

Bloody urine

Complete blood count (CBC), which determines the number, size, volume, and hemoglobin content of red blood cells

Blood iron level and your serum ferritin level, the best indicators of your body's total iron stores

Levels of vitamin B12 and folate, vitamins necessary for red blood cell production

Special blood tests to detect rare causes of anemia, such as an immune attack on your red blood cells, red blood cell fragility, and defects of enzymes, hemoglobin, and clotting

Reticulocyte count, bilirubin, and other blood and urine tests to determine how quickly your blood cells are being made or if you have a hemolytic anemia, where your red blood cells have a shortened life span

Only in rare cases will a doctor need to remove a sample of bone marrow to determine the cause of your anemia. 

Symptoms that may include: Pale appearance Jaundice, including elevated bilirubin Enlarged liver or spleen Swelling of the entire body Difficulty breathing A DAT will be ordered when there are signs and symptoms of a blood transfusion reaction, such as: Fever, chills Back pain Bloody urine

Complete blood count (CBC), which determines the number, size, volume, and hemoglobin content of red blood cells

Blood iron level and your serum ferritin level, the best indicators of your body's total iron stores

Levels of vitamin B12 and folate, vitamins necessary for red blood cell production

Special blood tests to detect rare causes of anemia, such as an immune attack on your red blood cells, red blood cell fragility, and defects of enzymes, hemoglobin, and clotting

Reticulocyte count, bilirubin, and other blood and urine tests to determine how quickly your blood cells are being made or if you have a hemolytic anemia, where your red blood cells have a shortened life span

Only in rare cases will a doctor need to remove a sample of bone marrow to determine the cause of your anemia. 

Test Method 1 : A sample of your blood will be needed to perform the test. The blood is tested with compounds that will react with antibodies in your blood. 

The blood sample is obtained through ñvenipuncture, î in which a needle is inserted into a vein in your arm or hand. The needle draws a small amount of blood into tubing, and the sample is stored in a test tube. 

 

This test is often done on infants who may have antibodies in their blood because their mother has a different blood type. To do this test in an infant, the skin is pricked with a small sharp needle called a lancet, usually on the heel of the foot. Blood is collected into a small glass tube, on a glass slide, or on a test strip. 

Report available : Turn around time is 24 hours. 

A person have the following signs and symptoms should get this done:    Symptoms that may include: 

Pale appearance

Jaundice, including elevated bilirubin

Enlarged liver or spleen

Swelling of the entire body

Difficulty breathing

A DAT will be ordered when there are signs and symptoms of a blood transfusion reaction, such as: 

Fever, chills

Back pain

Bloody urine

Hemolytic anemia, Chronic lymphocytic leukemia Infectious mononucleosis, Mycoplasmal infection, Syphilis, Systemic lupus erythematosus