penicillin V – Uses, Warnings & Side effects!

Penicillin V is a prescription drug that comes as an oral tablet and an oral solution. Penicillin V oral tablet is only available as a generic drug.

Why it’s used

Penicillin V oral tablet is used to treat certain infections caused by bacteria. It won’t work to treat infections caused by viruses, such as the common cold. Bacterial infections this drug is used to treat include:

  • streptococcal upper respiratory tract infections, scarlet fever, and erysipelas infections
  • pneumococcal upper respiratory infections
  • staphylococcal skin and soft tissue infections
  • fusospirochetosis (infection of the oropharynx or middle part of the throat)
  • prevention of rheumatic fever and chorea

This drug may be used as part of combination therapy. This means you may need to take it with other medications.

How it works

Penicillin V belongs to a class of drugs called antibiotics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Penicillin V works by stopping the bacteria from multiplying. This kills off the bacteria that are causing your infection.

Penicillin V side effects

Penicillin V oral tablet doesn’t cause drowsiness. However, it may cause other side effects.

More common side effects

The more common side effects of penicillin V can include:

  • nausea
  • vomiting
  • stomach upset
  • diarrhea
  • black hairy tongue

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Allergic reaction. Symptoms can include:
    1. skin rash with or without blisters
    2. flu-like symptoms, such as a fever, feeling ill, or joint pain
    3. swelling of your throat, tongue, or mouth
  • Diarrhea. Symptoms include:
    1. bloody or watery diarrhea with or without stomach cramps and a fever


Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

penicillin V

Penicillin V may interact with other medications

Penicillin V oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.


Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

How to take penicillin V

This dosage information is for penicillin V oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • the severity of your condition
  • other medical conditions you have
  • how you react to the first dose

Take as directed

Penicillin V oral tablet is used for short-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all:

Your infection may not get better or may get worse. Even if you’re starting to feel better, you should still finish all of your medication.

If you miss doses or don’t take the drug on schedule:

Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much:

You could have dangerous levels of this drug in your body. Symptoms of an overdose of this drug can include:

  • Diarrhea
  • Nausea
  • Oral infection.

Symptoms can include:

  1. creamy white lesions that look like cottage cheese
  2. cottonmouth (dry mouth)
  • Vomiting
  • Blackened tongue

What to do if you miss a dose:

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working:

Your symptoms and your infection should get better.

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