Anti CCP-Anti Cyclic Citrullinated Peptide Antibody test

This antibody test is primarily ordered along with an Rheumatoid Arthritis test when someone is detected with signs and symptoms that may be due to previously undiagnosed inflammatory arthritis. It is also adviced for someone who has been diagnosed with undifferentiated arthritis in the previous test. For some individuals, it is suggested as a follow-up test to a negative Rheumatoid Factor test. Because there may be clinical signs and symptoms that lead your doctor to suspect Rheumatoid Arthritis. Rheumatoid Arthritis (RA) normally affects multiple joints symmetrically.

Signs and symptoms include: 

Pain sometimes affects the neck, elbows, hips, shoulders, knees, and feet

Feeling of Stiffness of affected joints in the morning hours, but improves during the course of the day

Growth of nodules under the skin, especially at the elbows

A general feeling of being unwell (malaise)

Joint pain

Joint swelling

Joint tenderness

Joint warmth

Joint redness

Loss of joint range of motion

Joint stiffness

When the presence of Cyclic Citrullinated Peptide (CCP) antibody found in the test,  it means the result is positive. People with signs and symptoms of arthritis are found positive for both CCP antibody and RF, it is likely that they have RA. 

And is likely that RA may develop in a more rapidly progressive and severe form of a disease. When people are found positive only for CCP antibody but not RF, or both have low levels and also has clinical signs suggesting RA, then it is more likely that they have an early stage of RA.

When individuals are found negative for CCP antibody but detected with a positive RF, then the clinical symptoms and signs are more vital in determining whether they have RA or some other inflammatory condition.

When someone is tested negative for both CCP antibody and RF, then it is less likely that the person has RA. It must be emphasized that RA is a type of clinical diagnosis and may be made in the absence of positive tests for autoantibodies.

You are advised to consult your doctor to inform about your ongoing medications if there is any. The medications can alter the test results. Avoid the intake of multivitamins or any type of dietry supplements if your consuming any before the test.

The treatment varies from person to person depending on the health status and your medical history.

Doctors prescribe medications, therapy, and surgery depending on the requirement as per the patient medical history.

The type of medications referred buy the doctor includes:

Nonsteroidal anti-inflammatory drugs: It helps to relieve your pain and reduces inflammation.

Steroids: It helps to reduce slow joint damage, inflammation, and pain.

Disease-modifying antirheumatic drugs: It helps to slow down the progression of rheumatoid arthritis and save the joints with other tissues from any permanent damage. 

Biologic response modifiers: It is a new invention in the field of medication in treating Cyclic Citrullinated Peptide antibody. It is also a part of disease-modifying antirheumatic drugs.

Therapy is suggested by the doctor to relieve your pain through particular exercises and assistive devices that help it easier in stressing your joints.

Surgery is advised when a patient is not responding well to medication treatment. The surgery will help in repairing any damaged joints and improve the functioning by reducing pain. 

Test Method 1: Anti Cyclic Citrullinated Peptide Antibody is a type of blood test. A small amount of blood is drawn from a vein of your arm.

Report available: The turn around time for the test is around 24 hours.

In most of the cases, doctors prescribe this test along with another test called Rheumatoid factor test. 

Also, when individuals suffering from symptoms of arthritis and systematic autoimmune disease.

 

 

Rheumatoid Arthritis