ACTH-Adreno Corticotrophic Hormone test

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Know more about ACTH-Adreno Corticotrophic Hormone test

The ACTH-Adreno Corticotrophic Hormone test helps to diagnose adrenal gland problems and pituitary disease. It include cushing syndrome and disease, adrenal insifficiency and tumors and putuitary tumors. In general, ACTH level increases when cortisol level is low and decreases when cortisol level is high. Conditions affecting the hypothalamus, pituitary or adrenal glands can intervene with regulating ACTH and cortisol production. It goes high or falls low depending on how much of the hormones the glands produce.

The symptoms of high cortisol level: 

obesity with a rounded face

fragile and thin skin

purple lines on the abdomen

weak muscles

acne

increased amount of body hair

high blood pressure

low potassium level

high bicarbonate level

high glucose levels leading to diabetes. 

The symptoms of low cortisol include: 

weak muscles

fatigue

gradual weight loss

increased skin pigmentation in those areas not exposed to the sun

loss of your appetite

low blood pressure

low blood glucose levels

 Adreno Corticotrophic Hormone is a type of hormone that stimulates the production of Cortisol. In general, Adreno Corticotrophic Hormone levels raises when cortisol is low and falls when cortisol is increased. 

Conditions affecting the hypothalamus, pituitary or adrenal glands can intervene in regulating cortisol production.  It helps to know how much of the hormones the glands produce with increasing or decreasing of cortisol. 

Cushing’s disease is an ectopic tumor. It produces ACTH adrenoleukodystrophy, a rare Nelson’s syndrome. 

The low level of ACTH may be a sign of: 

adrenal tumor

exogenous Cushing’s syndrome

hypopituitarism

There are few preventive methods that needs to follow before going in for the test. Avoid the intake of food and drink for overnight before the test. Stop taking steroids if you normally consuming it. Avoid your regular excercise for 12 hours before taking the test. Inform your doctir you are taking any other medicatins, supplements or any vitamins. Accordingly your doctor will advise you the steps to follow before the test. Your doctor might even ask you for less consumption of carbohydrates 48 hours before the test.

The treatment for Addison's disease involves the hormone replacement therapy to correct the levels of steroid hormones your body isn't producing.

Some options for treatment include: 

Oral corticosteroids are:

Hydrocortisone (Cortef)

prednisone or cortisone acetate are used to replace cortisol.

Your doctor may prescribe fludrocortisone to replace aldosterone. 

Corticosteroid injections:

If your ill and facing frequent vomiting, instead of oral medications you will be prescribed for injections.

Test Method 1 : A small amount of blood will be collected through a small needle by pricking in your vein of the arm. And collects the blood sample in a small tube and gets transferred to the lab. 

Report available: The normal turn around time for the test is 24 hours.

 

Individuals who are likely experiencing the symptoms of Cushing disease should go for this test.